Category: Immunology/pets

Life and Death, the Cytokine Impact

Posted On By Christopher Lee DVM MPH DACVPM5 Comments
VetZone vet zone dog cat veterinary medicine veterinarian technician tech health CE continuing education preventive diplomate ACVPM DACVPM health Christopher Anthony Lee Kayla Wells MPH DVM Duration of Immunity vaccines IL-1 IL-6 IL-8 interleukin Tumor Necrosis Factor cytokine cytokines storm release syndrome IL6 IL1 HMGB1 high mobility Group Box Punic War Carthage Rome Julius Caesar septic shock decreased cardiac output decreased peripheral resistance Acute Respiratory Distress Syndrome ARDS and Disseminated Intervascular Coagulation DIC adjuvant

Like the ancient Roman army, cytokines are a formidable force When facing Carthaginian forces on the field of battle, Roman infantry proved devastating and impactful. When loitering within their own city walls, the Roman infantry also proved devastating and impactful, quickly leading the rule that the army must remain well outside their own city. A […]

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Category: Immunology/One Health/pets

Cytokine Storms, Stronger than World War I and Kublai Khan

Posted On By Christopher Lee DVM MPH DACVPMcomment
VetZone vet zone dog cat veterinary medicine veterinarian technician tech health CE continuing education preventive diplomate ACVPM DACVPM health Christopher Anthony Lee Kayla Wells MPH DVM Duration of Immunity vaccines Kublai Khan World War WWI cytokine cytokines storm release syndrome IL6 IL1 HMGB1 high mobility Group Box Shakespeare bodily body humors humor sanguine kamikaze Spanish flu h1n1

Kamikaze or “Divine Winds” twice saved Japan from the Mongolian Fleet Long before the current use of the word kamikaze, Japanese used “divine wind,” the name translation, in a literal sense. In the thirteenth century, the largest contiguous empire the world has ever seen sailed its formidable armada and all its might towards the shores […]

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Category: Administration

Duration of Immunity

Posted On By Christopher Lee DVM MPH DACVPMcomment
VetZone vet zone dog cat veterinary medicine veterinarian technician tech health CE continuing education preventive diplomate ACVPM DACVPM health Christopher Anthony Lee Kayla Wells MPH DVM Duration of Immunity vaccines prove 3 three 1 one 5 five year rabies distemper parvo feline panleukopenia leukemia Single Tier Label Claim veterinary biologics

The USDA recently announced a transition to Single Tier Label Claim for all veterinary biologics. Effective for all newly licensed vaccines, the decision retroactively applies to all currently licensed vaccines over the course of several years. This change promotes label clarity for both veterinarians and pet owners and reduces some of the competitive confusion between […]

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